Ezem Ezem (Hebrew: עצם, vars. ‛Atsem or Otzem, meaning strength) is an unidentified site in the Negeb of Judah toward the Edomite border. It is mentioned in the Biblical Book of Joshua(15:29; 19:1-3). In the King James Version it is spelled "Azem" in Joshua and "Ezem" in Chronicles (4:29).